Laboratory of Molecular Neuropsychoecoendochemistry
Our laboratory focuses on the impact of social and environmental stressors on molecular, neural and endocrine responses to influence adaptive behavior and activities like social interaction, learning, developing social rank relationships, depression, anxiety, biological rhythms, reproduction, and coping with stress. Of special interest are how and why individuals differ, and how responses are characterized temporally. The investigations include the connection between molecular, neural and endocrine responses and variability in the magnitude and way in which individuals respond to and cope with stress behaviorally. We have recently developed a new model that includes aggression, learned escape and conditioned submission. We are interested in elucidating the mechanisms by which experience modulates the responsiveness of neural and hormonal stress responses. We focus on the relationships of molecular genetics, physiology and anatomy with behavior, ecology and evolution.
Selected Lab Publications A complete listing of Lab publications
Arendt DH, J Hassell, Hao Li, JK Achua, DJ Guarnieri, RJ DiLeone, PJ Ronan, and CH Summers 2014 Anxiolytic function of the orexin 2 /
hypocretin A receptor in the basolateral amygdala. Psychoneuroendocrinology 40C: 17-26
Carpenter RE and CH Summers 2009 Learning strategies during fear conditioning Neurobiology of Learning and Memory 91: 415-423
Korzan WJ, E Höglund, MJ Watt, GL Forster, Ø Øverli, JL Lukkes and CH Summers 2007 Memory of opponents is more potent than visual sign
stimuli after social hierarchy has been established. Behav Brain Res 183: 31-42
Robertson JM, MA Prince, JK Achua, RE Carpenter, DH Arendt, JP Smith, TL Summers, TR Summers, and CH Summers 2015 Nuance and behavioral
cogency: How the Visible Burrow System inspired the Stress-Alternatives Model and conceptualization of the continuum of anxiety.
Physiology and Behavior 146: 86-97
Ronan PJ, MP Gaikowski, SJ Hamilton, KJ Buhl and CH Summers 2007 Ammonia causes decreased brain monoamines in fathead minnows (Pimephales
promelas). Brain Res 1147: 184-191
Smith JP, JK Achua, TR Summers, PJ Ronan and CH Summers 2014 Neuropeptide S and BDNF gene expression in the amygdala are influenced by social
decision-making under stress. Front Behav Neurosci 8:121: 1-13 doi: 10.3389/fnbeh.2014.00121
Ten Eyck, GR, PJ Ronan, KJ Renner and CH Summers 2005 Serotonin metabolism in directly developing frog embryos during paternal care.
Neurosci Lett 388: 100-105
Waters RP, KJ Renner, CH Summers, MJ Watt, GL Forster, LG Koch, SL Britten, JG Swallow 2010 Selection for intrinsic endurance modifies endocrine
stress responsiveness Brain Res 1357: 53-61