Summers Lab

Laboratory of Molecular Neuropsychoecoendochemistry


Investigators                     Research                    Publications                     Cliff Summers                     Contact Us                    

PhD Student wanted

The Summers Lab at the University of South Dakota is recruiting a PhD Student to work on NIH Funded research. This research examines the intensity of anxiety in mice using the newly developed Stress-Alternatives Model (SAM). The questions focus on the orexin/hypocretin system as well as other neuromodulatory systems. Experience with intracranial injection is preferred, but not required. Use these web links to examine the funded research to be executed, and other research in our lab. Please contact Cliff Summers for inquires at cliff@usd.edu or 605-677-6177.
Research Interests
Our laboratory focuses on the impact of social and environmental stressors on molecular, neural and endocrine responses to influence adaptive behavior and activities like social interaction, learning, developing social rank relationships, depression, anxiety, biological rhythms, reproduction, and coping with stress. Of special interest are how and why individuals differ, and how responses are characterized temporally. The investigations include the connection between molecular, neural and endocrine responses and variability in the magnitude and way in which individuals respond to and cope with stress behaviorally. We have recently developed a new model that includes aggression, learned escape and conditioned submission. We are interested in elucidating the mechanisms by which experience modulates the responsiveness of neural and hormonal stress responses. We focus on the relationships of molecular genetics, physiology and anatomy with behavior, ecology and evolution.
Selected Lab Publications          A complete listing of Lab publications
Arendt DH, J Hassell, Hao Li, JK Achua, DJ Guarnieri, RJ DiLeone, PJ Ronan, and CH Summers 2014 Anxiolytic function of the orexin 2 / 
	hypocretin A receptor in the basolateral amygdala. Psychoneuroendocrinology 40C: 17-26

Carpenter RE and CH Summers 2009 Learning strategies during fear conditioning Neurobiology of Learning and Memory 91: 415-423

Korzan WJ, E Höglund, MJ Watt, GL Forster, Ø Øverli, JL Lukkes and CH Summers 2007 Memory of opponents is more potent than visual sign 
	stimuli after social hierarchy has been established. Behav Brain Res 183: 31-42

Robertson JM, MA Prince, JK Achua, RE Carpenter, DH Arendt, JP Smith, TL Summers, TR Summers, and CH Summers 2015 Nuance and behavioral
	cogency: How the Visible Burrow System inspired the Stress-Alternatives Model and conceptualization of the continuum of anxiety. 
	Physiology and Behavior 146: 86-97

Ronan PJ, MP Gaikowski, SJ Hamilton, KJ Buhl and CH Summers 2007 Ammonia causes decreased brain monoamines in fathead minnows (Pimephales 
	promelas). Brain Res 1147: 184-191

Smith JP, MA Prince, JK Achua, JM Robertson, RT Anderson, PJ Ronan, and CH Summers 2016 Intensity of anxiety is modified via complex 
	integrative stress circuitries. Psychoneuroendocrinology 63: 351-361

Ten Eyck, GR, PJ Ronan, KJ Renner and CH Summers 2005 Serotonin metabolism in directly developing frog embryos during paternal care. 
	Neurosci Lett 388: 100-105

Waters RP, M Rivalan, D Bangasser, J Deussing, M Ising, SK Wood, F Holsboer, CH Summers 2015 Evidence for the role of 
	corticotropin-releasing factor in major depression disorder Neuroscience & Biobehavioral Reviews 63: 351-361

Neuroscience Group at USD                     Biology Department                     Summers' Biology Webpage                     Summers' Course Offerings                     Contact Us                     USD